Research

Our publications are all open access. If repositories are not provided with the citation below, please contact us so we can share them with you.

Highlighted

A stable, distributed code for cue value in mouse cortex during reward learning

David J. Ottenheimer, Madelyn M. Hjort, Anna J. Bowen, Nicholas A. Steinmetz, Garret D. Stuber

eLife  ·  30 May 2023  ·  https://doi.org/10.7554/eLife.84604

Examines the distribution of value-coding neurons across prefrontal cortex, combining electrophysiology and 2-photon calcium imaging. Dataset available for download.

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open-science collaboration

Topographic representation of current and future threats in the mouse nociceptive amygdala

Anna J. Bowen, Y. Waterlily Huang, Jane Y. Chen, Jordan L. Pauli, Carlos A. Campos, Richard D. Palmiter

Nature Communications  ·  13 Jan 2023  ·  https://doi.org/10.1038/s41467-023-35826-4

Identified topographic differences in coding of current external versus internal threats in central amygdala CGRP-receptor expressing neurons.

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2025

Single-cell sequencing of rodent ventral pallidum reveals diverse neuronal subtypes with noncanonical interregional continuity

David J. Ottenheimer, Rhiana C. Simon, Brandy A. Briones, Cassidy T. Burke, Anna J. Bowen, Susan M. Ferguson, Garret D. Stuber

Science Advances  ·  05 Dec 2025  ·  https://doi.org/10.1126/sciadv.adp3059

collaboration

Neuropixels Opto: Combining high-resolution electrophysiology and optogenetics

Anna Lakunina, Karolina Z. Socha, Alexander Ladd, Anna J. Bowen, Susu Chen, …, Timothy D. Harris, Nicholas A. Steinmetz, Karel Svoboda, Joshua H. Siegle, Matteo Carandini

bioRxiv  ·  15 Oct 2025  ·  https://doi.org/10.1101/2025.02.04.636286

collaboration preprint

2024

Simultaneous mesoscopic measurement and manipulation of mouse cortical activity

Pascha Matveev, Anna J. Li, Zhiwen Ye, Anna J. Bowen, Ximena Opitz-Araya, Jonathan T. Ting, Nicholas A. Steinmetz

bioRxiv  ·  01 Nov 2024  ·  https://doi.org/10.1101/2024.11.01.621418

preprint

2023

A stable, distributed code for cue value in mouse cortex during reward learning

David J. Ottenheimer, Madelyn M. Hjort, Anna J. Bowen, Nicholas A. Steinmetz, Garret D. Stuber

eLife  ·  30 May 2023  ·  https://doi.org/10.7554/eLife.84604

Examines the distribution of value-coding neurons across prefrontal cortex, combining electrophysiology and 2-photon calcium imaging. Dataset available for download.

Manuscript Source

download data

open-science collaboration

Parabrachial tachykinin1-expressing neurons involved in state-dependent breathing control

Joseph W. Arthurs, Anna J. Bowen, Richard D. Palmiter, Nathan A. Baertsch

Nature Communications  ·  21 Feb 2023  ·  https://doi.org/10.1038/s41467-023-36603-z

collaboration

Topographic representation of current and future threats in the mouse nociceptive amygdala

Anna J. Bowen, Y. Waterlily Huang, Jane Y. Chen, Jordan L. Pauli, Carlos A. Campos, Richard D. Palmiter

Nature Communications  ·  13 Jan 2023  ·  https://doi.org/10.1038/s41467-023-35826-4

Identified topographic differences in coding of current external versus internal threats in central amygdala CGRP-receptor expressing neurons.

download data

2022

A stable, distributed code for cue value in mouse cortex during reward learning

David J. Ottenheimer, Madelyn M. Hjort, Anna J. Bowen, Nicholas A. Steinmetz, Garret D. Stuber

openRxiv  ·  16 Jul 2022  ·  doi:10.1101/2022.07.13.499930

2020

Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons

Anna J. Bowen, Jane Y. Chen, Y. Waterlily Huang, Nathan A. Baertsch, Sekun Park, Richard D. Palmiter

eLife  ·  28 Aug 2020  ·  https://doi.org/10.7554/eLife.59799

Parsed the network downstream of parabrachial CGRP neurons and how activity is added to give rise to distinct physiological and behavioral states and learning.

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open-science

Chronic G _q signaling in AgRP neurons does not cause obesity

Sedona N. Ewbank, Carlos A. Campos, Jane Y. Chen, Anna J. Bowen, Stephanie L. Padilla, Joseph L. Dempsey, Julia Yue Cui, Richard D. Palmiter

Proceedings of the National Academy of Sciences  ·  25 Aug 2020  ·  https://doi.org/10.1073/pnas.2004941117

Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons

Anna J. Bowen, Jane Y. Chen, Y. Waterlily Huang, Nathan A. Baertsch, Sekun Park, Richard D. Palmiter

openRxiv  ·  12 Jun 2020  ·  doi:10.1101/2020.06.11.145987

2019

Parabrachial Complex: A Hub for Pain and Aversion

Michael C. Chiang, Anna Bowen, Lindsey A. Schier, Domenico Tupone, Olivia Uddin, Mary M. Heinricher

The Journal of Neuroscience  ·  16 Oct 2019  ·  https://doi.org/10.1523/jneurosci.1162-19.2019

review

2018

Encoding of danger by parabrachial CGRP neurons

Carlos A. Campos, Anna J. Bowen, Carolyn W. Roman, Richard D. Palmiter

Nature  ·  01 Mar 2018  ·  https://doi.org/10.1038/nature25511

Revealed unified activation of parabrachial CGRP neurons by multi-modal threats, including somatic pain, itch, visceral malaise – in addition to satiety and conditioned fear.

2017

Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus

Carlos A. Campos, Anna J. Bowen, Sung Han, Brent E. Wisse, Richard D. Palmiter, Michael W. Schwartz

Nature Neuroscience  ·  01 Jul 2017  ·  https://doi.org/10.1038/nn.4574

2016

Parabrachial CGRP Neurons Control Meal Termination

Carlos A. Campos, Anna J. Bowen, Michael W. Schwartz, Richard D. Palmiter

Cell Metabolism  ·  01 May 2016  ·  doi:10.1016/j.cmet.2016.04.006